Participating Companies

4SC AG [VSC:DB] €16 MM MCap
An epi­ge­net­ic fo­cused com­pany de­vel­op­ing small molecule drugs for the treat­ment of can­cer and au­toim­mune dis­eas­es. The com­pany’s lead com­pound, Res­mi­no­s­tat, is fo­cused on Cu­ta­neous T Cell Lym­pho­ma but has un­part­nered as­sets for Hod­kins Lym­pho­na, Col­orec­tal Can­cer, and HCC. [more in­for­ma­tion]
Achilles Therapeutics [ACHL] $93 MM MCap
cNeT (clo­n­al neoanti­gen) pro­cess builds on TILs, com­bined with abil­i­ty to iden­ti­fy pt-spe­cif­ic clo­n­al neoanti­gens and gen­er­ate per­so­n­al­ized T-cell ther­a­pies. Sep19 GBP100 mil­lion Se­ries B w/ RA, Syn­co­na, For­bion, In­vus, Per­cep­tive + Red­mile. [more in­for­ma­tion]
Anavex Life Sciences Corp. [AVXL] $849 MM MCap
The anal­y­sis of RNA and whole ex­ome DNA genome se­quenc­ing da­ta has char­ac­ter­ized sev­er­al ge­nom­ic al­ter­a­tions in well-char­ac­ter­ized tar­gets that can be used as bio­mark­ers to iden­ti­fy op­ti­mal pa­tients in forth­com­ing clin­i­cal trials (Rett, Alzheimer’s, and Parkin­son’s). [more in­for­ma­tion]
Apeiron Investment Group LLC
Ape­iron fo­cus­es on Fi­nan­cial Ser­vices (es­pe­cial­ly fin­tech and cryp­to as­sets), Tech­nol­o­gy, Life Sci­ences, Me­dia & En­ter­tain­ment and Re­al Es­tate & Prop-Tech. They in­vest in all phas­es and stages of a com­pany’s life cy­cle, but fo­cus on non-list­ed Seed/Start-up in­vest­ments and larg­er size Re­struc­tur­ing & Spe­cial Si­t­u­a­tions deals (of­ten list­ed). [more in­for­ma­tion]
Bain Capital Life Sciences
Bain Cap­i­tal Life Sci­ences in­vests in bio­phar­ma­ceu­ti­cal, spe­cial­ty phar­ma­ceu­ti­cal, med­i­cal de­vice, di­ag­nos­tics and en­abling life sci­ence tech­nol­o­gy com­pa­nies glob­al­ly, with a fo­cus on com­pa­nies that both drive med­i­cal in­no­va­tion across the val­ue chain and en­able that in­no­va­tion to im­prove the lives of pa­tients with un­met med­i­cal needs. [more in­for­ma­tion]
BioNTech AG [BNTX] $33,294 MM MCap
Through its di­ver­si­fied tech­nol­o­gy plat­forms and in-house di­ag­nos­tics and man­u­fac­tur­ing units, BioN­Tech is strate­g­i­cal­ly po­si­tioned to im­ple­ment its lab-bench-to-mar­ket strat­e­gy. [more in­for­ma­tion]
BlueStar Investment Managers SA (Onelife Advisors)
BlueS­tar is an as­set ma­n­age­ment com­pany head­quar­tered in Lugano, Switz­er­land, spe­cial­is­ing in ma­n­ag­ing in­vest­ment funds and ad­vis­ing in­sti­tu­tio­n­al clients on as­set al­lo­ca­tion, the­mat­ic in­vest­ments and in­vest­ment so­lu­tions. [more in­for­ma­tion]
Calliditas Therapeutics [CALT] $430 MM MCap
Cal­lid­i­tas Ther­a­peu­tics is a com­mer­cial stage bio­phar­ma com­pany based in Stock­holm, Swe­den fo­cused on iden­ti­fy­ing, de­vel­op­ing and com­mer­cial­iz­ing nov­el treat­ments in or­phan in­di­ca­tions, with an ini­tial fo­cus on re­nal and he­p­at­ic dis­eas­es with sig­ni­f­i­cant un­met med­i­cal needs. [more in­for­ma­tion]
CFGI
CF­GI - a port­fo­lio com­pany of The Car­lyle Group - is an estab­lished na­tio­n­al lead­er in pro­vid­ing op­er­a­tio­n­al fi­nance and tech­ni­cal ac­count­ing ser­vices. [more in­for­ma­tion]
Crescendo Biologics
Cres­cen­do Bi­o­log­ics is a clin­i­cal stage com­pany de­vel­op­ing T cell en­hanc­ing ther­a­peu­tics. Cres­cen­do’s lead pro­gramme, CB307, is a CD137 (4-1BB) x PS­MA bis­pe­cif­ic. CB307’s unique for­mat de­liv­ers tu­mour-spe­cif­ic killing, while avoid­ing sys­temic toxic­i­ty, and can be ap­plied to a broad range of PS­MA-pos­i­tive can­cer in­di­ca­tions. It is de­signed to cause the pro­lif­er­a­tion of tu­mour-spe­cif­ic T cells, cre­at­ing a safe, broad, longer-last­ing an­ti-tu­mour re­sponse and will be in the clin­ic in ear­ly 2021. [more in­for­ma­tion]
CureVac AG [CVAC] $1,571 MM MCap
Ger­man mR­NA com­pany with a di­ver­si­fied pipe­line; Ph 2a trial on­go­ing with COVID-19 vaccine can­di­date, CVn­CoV. Glob­al Ph 2/3 trial en­rolling ap­prox. 36,500 par­ti­ci­pants with re­sults ex­pect­ed 1Q21. Three other pro­grams in Ph 1: CV8102 (cu­ta­neous me­lano­ma, ade­noid­cys­tic car­ci­no­ma, squa­mous cell can­cer of skin, head & neck), CV9202 (NS­CLC) and CV7202 (Ra­bies). mR­NA-based anti­body de­liv­ery deal with Genmab (Dec'19). Other strate­g­ic part­n­er­ships in­clude GSK and CRIS­PR Tx. [more in­for­ma­tion]
Ernst & Young
Ernst & Young Limit­ed is a glob­al lead­er in as­su­r­ance, tax, tran­s­ac­tion and ad­vi­so­ry ser­vices. [more in­for­ma­tion]
Ethris
Ethris is pi­oneer­ing the de­vel­op­ment of next-gen­er­a­tion mR­NA ther­a­peu­tics and vaccines for re­s­pi­ra­to­ry dis­eas­es and in­fec­tions with high un­met needs. [more in­for­ma­tion]
Glycostem Therapeutics
Gly­costem Ther­a­peu­tics is a Dutch biotech com­pany. Gly­costem Ther­a­peu­tics is the trade name of the le­gal en­ti­ty IPD Ther­a­peu­tics BV, which has been estab­lished in De­cem­ber 2007. Gly­costem Ther­a­peu­tics has de­vel­oped the world's first GMP com­pliant NK-cell plat­form that is ready for in­dus­trial scale-up. [more in­for­ma­tion]
Goodwin Procter LLP
More than 1,000 cor­po­rate and liti­ga­tion at­tor­neys lev­er­age their spe­cif­ic ex­pe­ri­ence and as­sem­ble full-ser­vice teams to ad­vise clients in th­ese and ad­ja­cent in­dus­tries. [more in­for­ma­tion]
H.C. Wainwright & Co., LLC
Wain­wright & Com­pany, Inc. is a full-ser­vice in­vest­ment bank that of­fers equi­ty re­search ser­vices to in­sti­tu­tio­n­al and re­tail in­ves­tors. Wain­wright & Com­pany, Inc was estab­lished in 1868 and is head­quar­tered in New York Ci­ty. Rod­man & Ren­shaw is a sell side re­search wing of H.C. [more in­for­ma­tion]
Heights Capital Management, Inc.
Heights Cap­i­tal Ma­n­age­ment, Inc. is a San Fran­cis­co based pri­vate equi­ty firm spe­cial­iz­ing in pri­vate in­vest­ments in public equi­ty in emerg­ing growth com­pa­nies. [more in­for­ma­tion]
Immatics NV [IMTX] $656 MM MCap
Im­mat­ics com­bines the dis­cov­ery of true tar­gets for can­cer im­munother­a­pies with the de­vel­op­ment of the right T cell re­cep­tors with the goal of en­abling a ro­bust and spe­cif­ic T cell re­sponse against th­ese tar­gets. We are com­mitt­ed to de­liv­er­ing the pow­er of T cells and to un­lock­ing new av­enues for pa­tients in their fight against can­cer. [more in­for­ma­tion]
InflaRx N.V. [IFRX] $120 MM MCap
Com­ple­ment sys­tem fo­cused com­pany, de­vel­op­ing an­ti C5a mAbs with ap­pli­ca­tions in com­plex car­di­ac surgery, hi­dra­denits, AN­CA as­soc. Re­port­ed pos­i­tive Ph2a re­sults with IFX-1 in Jan­uary 2015. Fol­low-on molecule, IFX-2, in pre-clin­i­cal de­vel­op­ment for ad­di­tio­n­al sub-acute, chron­ic in­flam­ma­to­ry in­di­ca­tions. [more in­for­ma­tion]
invIOs
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iOnctura
iOnc­tu­ra is a clin­i­cal-stage com­pany ap­p­ly­ing in­sights in can­cer bi­ol­o­gy to de­vel­op high­ly se­lec­tive drugs that can si­mul­ta­ne­ous­ly in­hib­it mul­ti­ple tu­mor sur­vi­val mech­anisms. iOnc­tu­ra’s drug de­vel­op­ment pro­grams com­bine im­mune-me­di­at­ed and di­rect an­ti-tu­mor ac­tiv­i­ty to de­liv­er molecules with su­pe­ri­or clin­i­cal ef­fi­ca­cy and safe­ty in on­col­o­gy. [more in­for­ma­tion]
KBio
Cre­at­ing the new gen­er­a­tion of bi­o­log­ics us­ing its plant-based plat­form that has de­mon­s­trat­ed an abil­i­ty to cre­ate po­ten­tial­ly bet­ter anti­body drug can­di­dates at a frac­tion of the time and cost of cur­rent mam­malian cell-based anti­body plat­forms. The Com­pany is fo­cused on de­vel­op­ing nov­el prod­uct can­di­dates in two core ar­eas: 1) Anti­body ther­a­pies for ar­eas of high un­met need 2) Pan­dem­ic pre­pared­ness and re­sponse us­ing its plant-based pro­duc­tion sys­tem to rapid­ly cre­ate anti­bodies and vaccines. [more in­for­ma­tion]
Medigene AG [MDG1:DB] €47 MM MCap
blue­bird bio col­lab; BLUE ini­ti­at­ing trial w/MDG MAGEA-4 can­di­date in 2020. TCRs tar­get­ing HA-1 & MAGE-A1 in de­vt. . DC vax in on­go­ing Ph 1/2; fi­nal read­out in 2019. [more in­for­ma­tion]
Monte Rosa Therapeutics [GLUE] $389 MM MCap
Next-gen­er­a­tion molec­u­lar glue-based tar­get­ed pro­tein degra­da­tion plat­form de­vel­op­ing small molecule ther­a­peu­tics that se­lec­tive­ly de­grade dis­ease-caus­ing pro­teins. Tar­get­ing the un­drug­gable pro­teome in on­col­o­gy and non-on­col­o­gy in­di­ca­tions via AI based de­gron pre­dic­tion. Lead pro­gram fo­cused on GSP­T1, a key reg­u­la­tor and vul­n­er­a­bil­i­ty of Myc-in­duced trans­la­tio­n­al ad­dic­tion. [more in­for­ma­tion]
MorphoSys AG [MOR] $731 MM MCap
Its part­nered dis­cov­ery seg­ment ap­plies the re­search, de­vel­op­ment, and op­ti­miza­tion of anti­body-drug can­di­dates in part­n­er­ships with phar­ma­ceu­ti­cal and biotech­nol­o­gy com­pa­nies. In its pro­pri­e­tary de­vel­op­ment seg­ment, the com­pany de­vel­ops anti­bodies that con­cen­trate on in­flam­ma­to­ry and au­toim­mune dis­eas­es, as well as can­cer and in­fec­tious dis­eas­es. [more in­for­ma­tion]
Nasdaq, Inc. [NDAQ] $28,817 MM MCap
Nas­daq is pri­mar­i­ly known for its equi­ty exchange, but in ad­di­tion to its mar­ket ser­vices busi­ness (about 35% of sales), the com­pany sells and dis­tributes exchange da­ta through its in­for­ma­tion ser­vices seg­ment (30%). In­for­ma­tion ser­vices of­fers Nas­daq-brand­ed in­dex­es to as­set ma­n­agers and in­ves­tors. [more in­for­ma­tion]
NautaDutilh
Found­ed in 1724, Nau­ta­Du­tilh has grown to be­come one of the largest in the Benelux with over 400 lawy­ers, civ­il law no­taries and tax ad­vis­ers at of­fices in Am­s­ter­dam, Brus­sels, Lon­don, Lux­em­bourg, New York and Rot­ter­dam. It al­lows Nau­ta­Du­tilh lawy­ers to deal with change, learn from new si­t­u­a­tions and think on their feet when solv­ing problems on be­half of our clients. [more in­for­ma­tion]
Nykode Therapeutics [NYKD:OL]
Ap­prox­i­mate $1.1B mar­ket cap, clin­i­cal stage im­munother­a­py com­pany fo­cused on can­cer and in­fec­tious dis­ease. Mo­d­u­lar vaccine tech­nol­o­gy tar­gets anti­gens to Anti­gen Pre­sent­ing Cells to achieve rapid, strong and long-last­ing im­mune re­spons­es. Key pro­grams in­clude Ph2 pro­pri­e­tary HPV 16+ cer­vi­cal can­cer ther­a­peu­tic vaccine, Ph2 in­di­vi­d­u­al­ized can­cer neoanti­gen vaccine (Ge­nen­tech), Ph1/2 next-gen­er­a­tion COVID-19 T-cell vaccines. Sig­ni­f­i­cant col­lab­o­ra­tions with Re­generon, Ge­nen­tech, Adap­tive Biotech­nolo­gies. [more in­for­ma­tion]
Oryzon Genomics [ORY]
Tar­get­ing ly­sine spe­cif­ic demethy­lase 1 (LS­D1, aka KD­M1A). Lead CNS com­pound in 3 Phase 2a trials in MS, AD and bas­ket trial. Onc com­pound in 2 com­bo Phase 2a trials in AML and SCLC. Da­ta exp mid-2019 [more in­for­ma­tion]
Phenex Pharmaceuticals AG
Phenex is a pri­vate­ly held drug dis­cov­ery and de­vel­op­ment com­pany head­quar­tered in Lud­wigshafen with a ma­jor re­search site in Hei­del­berg. It is the com­pany ́s goal to part­n­er and out­li­cense drug pro­grams in ar­eas with ma­jor mar­ket po­ten­tial to glob­al play­ers from the bio­phar­ma­ceu­ti­cal in­dus­try while pur­su­ing own drug de­vel­op­ment in niche ar­eas with par­tic­u­lar high med­i­cal needs. [more in­for­ma­tion]
Priothera
Prio­thera is de­vel­op­ing the oral­ly ap­plied sphin­go­sine 1 phos­phate (S1P) re­cep­tor mo­d­u­la­tors for hae­ma­to­log­i­cal ma­lig­nan­cies. [more in­for­ma­tion]
PROSION
A phar­ma­ceu­ti­cal drug dis­cov­ery com­pany with pro­line de­rived mo­d­ules (ProMs) as the world’s first PRM struc­ture mim­ick­ing build­ing blocks. The com­pany de­vel­ops a new class of drugs and is able to ad­dress yet un­drug­gable con­sid­ered tar­gets that are re­lat­ed to vari­ous in­di­ca­tions. For its first of many use-cas­es, PRO­SION has al­ready shown a re­mark­able in vi­vo ef­fect of its ProM-based an­ti-me­tastat­ic in­hibi­tor – both in pan­cre­at­ic and breast can­cer xeno­graft ro­dent mod­els. [more in­for­ma­tion]
Silicon Valley Bank
Sil­i­con Val­ley Bank is a provider of com­mer­cial and pri­vate bank­ing ser­vices. The bank of­fers on­line and bank­ing ser­vices, pay­ments, de­posits and fraud pre­ven­tion ser­vices. Sil­i­con Val­ley Bank was found­ed in 1983 and is head­quar­tered in San­ta Clara, Cal­i­for­nia. [more in­for­ma­tion]
Solebury Strategic Communications
With al­most two de­cades of ex­pe­ri­ence in the biotech­nol­o­gy, phar­ma­ceu­ti­cal, med­i­cal tech­nol­o­gy and life sci­ence tech­nol­o­gy sec­tors, the Trout Group of­fers its clients the knowl­edge base need­ed to clar­i­fy in­vest­ment themes and lev­er­age key re­la­tion­ships for in­creased ex­po­sure to the prop­er au­di­ence. [more in­for­ma­tion]
SOTIO a.s.
The com­pany op­er­ates as a biotech­nol­o­gy firm which de­vel­ops new ther­a­pies to ad­dress un­met med­i­cal needs us­ing its im­munother­a­py plat­form and pro­pri­e­tary cell-based tech­nolo­gies, en­abling state-of-the-art im­munother­a­py treat­ment for its pa­tients in Prague, Czech Re­public. [more in­for­ma­tion]
SphingoTec GmbH
Sphin­goTec’s first-in-class tests are made avai­l­able on its pro­pri­e­tary whole-blood point-of-care Nexus IB10 plat­form for con­ve­nient and rapid test­ing in near-pa­tient and lab­o­ra­to­ry sett­ings along­side a broad port­fo­lio of stan­dard-of-care test for acute care. [more in­for­ma­tion]
sterna biologicals
By tar­get­ing tran­scrip­tion fac­tors that play a cen­tral role in reg­u­lat­ing Th1- and Th2-driv­en in­flam­ma­to­ry mech­anisms, the Com­pany’s pro­pri­e­tary DNAzyme-based drug can­di­dates can in­ter­vene with up­stream in­flam­ma­to­ry pro­cess­es to ad­dress re­lat­ed dis­eas­es more ef­fec­tive­ly. Ster­na cur­rent­ly has four pro­grams in phase 2 de­vel­op­ment. [more in­for­ma­tion]
Targovax [TRVX]
Pre­lim­i­nary Ph1b da­ta of OV ON­COS-102+che­mo in me­sothe­lio­ma re­sults: com­bo mPFS=8.4 mos. vs. con­trol mPFS=6.8 mos.; 1L pts mPFS-8.9 mos. Up­com­ing mile­s­tones: up­dat­ed clin­i­cal & im­mune da­ta in Ph2 me­sothe­lio­ma (1H20); pre­clin­i­cal da­ta on next-gen OV w/ dou­ble trans­genes (1H20); and clin­i­cal da­ta from Ph1 me­lano­ma study, part 2 with ex­tend­ed dos­ing (2H20). [more in­for­ma­tion]
Tonix Pharmaceuticals [TNXP] $26 MM MCap
The com­pany is en­gaged in dis­cov­er­ing, li­cens­ing, ac­quir­ing and de­vel­op­ing drugs and bi­o­log­ics to treat and pre­vent hu­man dis­ease and alle­vi­ate suf­fer­ing. Its port­fo­lio in­cludes bi­o­log­ics to pre­vent in­fec­tious dis­eas­es and small molecules and bi­o­log­ics to treat pain, psychi­a­tric and ad­dic­tion con­di­tions. [more in­for­ma­tion]
Vivoryon [VVY:AS] €213 MM MCap
De­vel­ops small molecule medicines that mo­d­u­late the ac­tiv­i­ty and sta­bil­i­ty of patho­log­i­cal­ly al­tered pro­teins. Lead can­di­date varog­lu­tam­s­tat, cur­rent­ly in VIVI­AD EU Ph2b and VI­VA-MIND US Ph2a/2b studies in Alzheimer’s dis­ease (AD), tar­gets all three ma­jor hall­marks of AD (Abe­ta pathol­o­gy, tau pathol­o­gy, neu­roin­flam­ma­tion) and sy­nap­tic im­pair­ment. [more in­for­ma­tion]
Wellington Partners
Found­ed in 1998, Welling­ton Part­n­ers is a ven­ture cap­i­tal firm based in Mu­nich, Ger­many. The firm seeks to in­vest in the ear­ly- and growth-stage tech­nol­o­gy and life sci­ence sec­tors. [more in­for­ma­tion]