Keros Therapeutics

Keros Therapeutics: A leader in understanding the role of the Transforming Growth Factor-Beta family of proteins that is a master regulator of red blood cell and platelet production as well as the growth, repair and maintenance of muscle and bone. Lead protein therapeutic product candidate, KER-050, an engineered ligand trap comprised of a modified ligand-binding domain of the TGF-β receptor known as activin receptor type IIA that is fused to the portion of the human antibody known as the Fc domain, is being developed for the treatment of cytopenias, including anemia and thrombocytopenia, in patients with myelodysplastic syndrome (MDS) and myelofibrosis. KER-012, is designed to bind to and inhibit the signaling of TGF-β ligands that suppress bone growth, including activin A and activin B and is being developed for the treatment of PAH and for the treatment of disorders associated with bone loss, such as osteogenesis imperfecta and osteoporosis.
Based in...
US - New England
Clinical Stage
Phase l or ll
Disease Space
Hematology, Metabolic Disorders, Oncology, Rare Disease
Public, USA
Market Cap
1B +
99 Hayden Avenue
Suite 120 (Building E)
Lexington, MA 02421
United States

Company Participants at Solebury Trout 1x1 Management Access Event 2022

  • Jasbir Seehra, CEO

Top 10 Holders of Keros Therapeutics, Inc.

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
Fidelity Management & Research Co. LLC 14.10 4,024,086 197.86 13F 3/31/23
OrbiMed Advisors LLC 5.89 1,679,417 82.58 13F 3/31/23
Alkeon Capital Management LLC (13F Subfiler) 5.03 1,435,532 70.59 13F 3/31/23
T. Rowe Price Associates, Inc. (Investment Management) 4.04 1,152,516 56.67 13F 3/31/23
The Vanguard Group, Inc. 3.56 1,015,436 49.93 Funds 4/30/23
Vanguard Group, Inc. (Subfiler) 3.51 1,001,115 49.22 13F 3/31/23
Alkeon Capital Management LLC 3.32 946,671 46.55 Funds 3/31/23
State Street Corp. 3.31 944,159 46.42 13F 3/31/23
Paradigm BioCapital Advisors LP 3.26 930,752 45.77 13F 3/31/23
BlackRock Fund Advisors 2.85 813,252 39.99 13F 3/31/23
Ownership data is sourced through FactSet.

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